Rheumatology Diagnostic Laboratory Information Page

Rheumatology Diagnostic Laboratory (RDL)

Contacts
To order tests, or for more information:
Barbara Rao, RDL Customer Service
(800) 338-1918

For technical information:
Erik Avaniss-Aghajani, Ph.D.
(800) 338-1918
erik@laragen.com

www.rdlinc.com

GENERAL INFORMATION

Assay Names	Genotype	ViroSeq™ HIV-1 Genotyping System (Applied Biosystems) TruGene™ HIV (Visible Genetics) [RDL test name = "Virotype"]
Collaborators/Distributors		Applied Biosystems, Visible Genetics
Availability		Commercially available for research use only.
Regulatory Status		ViroSeq™ HIV-1 and TruGene™ HIV are approved for "Investigational Use Only" under an FDA-approved IDE in CLIA certified labs. RDL is a CLIA-approved laboratory.
Proficiency Testing Programs		Content in development.
Clinical Trials		No
Financial Assistance		Approved Provider, California Department of Health, Office of AIDS HIV Resistance Testing Program.

ASSAY INFORMATION

Genotypic		Codons Interrogated
ViroSeq	TruGene	RT	PI
Full sequence	Full sequence	1–320 (ViroSeq) 40–247 (TruGene)	1–99

Turnaround Time		Sensitivity
ViroSeq	TruGene	ViroSeq	TruGene
10 days	7–14 days	500 RNA copies/mL	1,000 RNA copies/mL

METHODOLOGY

Genotype
RDL primarily uses the Applied Biosystems (formerly PE Biosystems) ViroSeq™ HIV-1 Genotyping System. Failed samples are re-run with the Visible Genetics TruGene™ HIV test.

REPORT INFORMATION

Report	Drug Resistance Interpretation
Genotype	Yes	Interpretation provided by request by the Stanford HIV RT and Protease Sequence Database Sequence Analyzer (beta test version)

Return to Test Information Table - Genotypic

Return to Test Information Table - Phenotypic