The matrix below highlights key and common point mutations associated with the development of antiretroviral drug resistance and cross-resistance to Nucleoside Reverse Transcriptase Inhibitors (NRTI). Resistance data are included only for FDA-approved drugs and drugs available through Expanded Access Programs.
Intermediate/
High Level
Resistance
Low Level Resistance
Contributes to Resistance
Unknown
No resistance
Increased Susceptibility
Click on drug names, colored cells and mutations for additional and specific data.
Increased Susceptibility
