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The matrix below highlights key and common point mutations associated with the development of antiretroviral drug resistance and cross-resistance to Non Nucleoside Reverse Transcriptase Inhibitors (NNRTI). Resistance data are included only for FDA-approved drugs and drugs available through Expanded Access Programs.

High Level Resistance Intermediate Level
Resistance
Low Level Resistance Unknown   No resistance

Increased Susceptibility

Click on drug names and colored cells for additional and specific data.
 
Nevirapine Delavirdine Efavirenz
mutation
A98G
L100I
K101E
K103N
K103R
V106A/!
V108I
V179D/E
Y181C/I
Y188C/L/H
G190A/S
P225H
M230L
P236L
Y318F
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